Melatonin

<span style="font-size: 18pt; line-height: 1.4; font-family: Arsenal;">Improve your sleep with Nutragenix MELATONIN Sublingual Spray Supplement.</span>
Discover the MELATONIN sublingual spray supplement by Nutragenix, the ideal solution to improve the quality of sleep and rest better. Just one spray under the tongue about 20 minutes before bedtime is enough to have a regenerating sleep.
<span style="font-size: 18pt; line-height: 1.4; font-family: Arsenal;">Regulate your sleep-wake cycle with melatonin.</span>
Melatonin is a natural hormone produced by our bodies that regulates our sleep-wake cycle. Nutragenix MELATONIN Sublingual Spray supplement helps regulate your circadian rhythm, improving sleep quality and reducing daytime fatigue.



<span style="font-size: 18pt; line-height: 1.4; font-family: Arsenal;">Rest better and wake up refreshed.</span>
Quality sleep is essential for your health and well-being. Nutragenix MELATONIN Sublingual Spray supplement helps improve the quality of your sleep, allowing you to rest better at night and wake up refreshed and energized.



<span style="font-size: 18pt; line-height: 1.4; font-family: Arsenal;">Advanced formula for optimal results.</span>
Nutragenix MELATONIN Sublingual Spray Supplement is made with micellar technology to ensure optimal results. Its high bioavailability ensures rapid assimilation and slow release of the ingredient during the night, promoting relaxation and sleep.



<span style="font-size: 18pt; line-height: 1.4; font-family: Arsenal;">Easy to take anywhere, anytime.</span>
Nutragenix MELATONIN Sublingual Spray is easy to take thanks to the convenient 15ml spray bottle that you can leave on your bedside table and store at room temperature. You can also take it with you when you travel. Just one spray under the tongue and you can be sure to get all the benefits of melatonin and improve the quality of your sleep.



<span style="font-size: 18pt; line-height: 1.4; font-family: Arsenal;">Quality and safety guaranteed.</span>
Nutragenix MELATONIN Sublingual Spray Supplement is made in Italy with premium ingredients and rigorously tested to ensure maximum efficacy and safety. With Nutragenix, you can be sure to get an effective, reliable and high-quality supplement to improve the quality of your sleep.

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<td> <strong>PRODUCT DESCRIPTION</strong>
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<td> Melatonin-based food supplement with new patented technology.
The beneficial effect of reducing the time required to fall asleep is obtained by taking 1 mg of Melatonin per day, the maximum dosage permitted in supplements, just before going to bed.</td>


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<td> <strong>FORMAT</strong>
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<td> 15 ml glass bottle with micropump and oral dispenser</td>


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<td> <strong>INGREDIENTS</strong>
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<td> Stabilizer: Glycerol, Demineralized water, Emulsifier: Polysorbate 80; Acidity regulators: Sodium bicarbonate; Emulsifier: Conjugated linoleic acid; Vanilla flavor, Melatonin.
<strong>GLUTEN FREE
</strong> <strong>NATURALLY LACTOSE FREE</strong>
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<td> <strong>HOW TO USE</strong>
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<td> It is recommended to spray 1 dose under the tongue just before going to sleep. Wait 30 seconds before swallowing. Shake the bottle before use.</td>


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<td> <strong>DAILY DOSE</strong>
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<td>One spray contains 1 mg of Melatonin. For a constant integration over time, we recommend 1 daily sublingual spray equal to 1 mg of Melatonin. Based on what has emerged from our laboratory tests, the technology used allows the principle administered sublingually to have an efficiency equal to 3 times that of free Melatonin, therefore the dosage should be compared with an alternative of 3 mg ( <a href="https://nutragenix.it/wp-content/uploads/2022/11/Studio-sulla-Melatonina-Emuldrop-Rev.1.8-italiano_bassa-copia.pdf" target="_blank" rel="noopener">Report Melatonin EMULDROP</a> , and <a href="https://nutragenix.it/wp-content/uploads/2022/11/ASSORBIMENTO-MELATONINA.pdf" target="_blank" rel="noopener">its absorption</a> )
Taking the dose of 1 spray per day, the bottle will last approximately 4 months.</td>


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<td> <strong>STORAGE METHODS</strong>
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<td>Store at room temperature in a cool, dry place. Avoid exposure to localized heat sources, sunlight and contact with water. The minimum shelf life refers to the product correctly stored, in intact packaging. Do not dispose of in the environment after use.</td>


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<td> <strong>HOW TO USE</strong>
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<td> Shake before use, spray one spray under the tongue. Wait at least 30 seconds before swallowing. To obtain the maximum effect of the ingredient (i.e. significantly increase its effectiveness up to 3 times) it is recommended not <strong>to eat for 40 minutes after spraying.</strong>
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<td> <strong>WARNINGS</strong>
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<td> Do not exceed the recommended daily dose. Food supplements should not be considered as a substitute for a varied, balanced diet and a healthy lifestyle. Keep out of reach of children under 3 years. Any dosage other than the recommended one should always be discussed with your doctor.</td>


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<td><strong>IMPORTANT</strong></td>

<td> Although in general there are no contraindications, it is not recommended in case of hypersensitivity or allergy to any of the components of the formulation.</td>


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<span style="font-size: 18pt; line-height: 1.4; font-family: Arsenal;">Melatonin is useful for:</span>
<ul>

<li> Improve sleep quality and circadian rhythm,</li>

<li> Increase nighttime GH levels</li>

<li> Jet lag</li>

<li> Reducing <a href="https://healthy.thewom.it/dipendenze/astinenza-nicotina/">Withdrawal Symptoms When Quitting Smoking</a>
</li>

<li> Strengthen the immune system</li>

<li> Fight body inflammation</li>

<li> Fight oxidative stress</li>

<li> Improve the aging process by slowing down the deterioration of organs</li>

<li> Prevent the onset of some tumors</li>

<li> Slowing down tumor progression</li>

<li> Improving the quality of life of cancer patients</li>

<li>Improve problems related to gastroesophageal reflux</li>

<li> Protect from neurodegenerative diseases</li>


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<strong>NutraGenix Melatonin Spray is much more effective than traditional oral forms.</strong>

While there are several ways to take Melatonin supplements such as drops, tablets, capsules, micro tablets, gummies and syrups, <strong>the sublingual spray is the most efficient method of delivering Melatonin to our body</strong> .

Melatonin is in fact known for its low and variable bioavailability in humans due to a high first-pass effect, variable pharmacokinetics and short half-life. With 10 mg of oral melatonin (drug dose), the bioavailability is actually 2.5% (Lars PH Andersen, 2016)

To avoid the first-pass effect responsible for a loss of up to 90% of the oral dose of melatonin (in 30-60 minutes) (V. Srinivasan, 2015) and to ensure a rapid onset of activity, NutraGenix proposes <strong>a new liquid sublingual emulsion in the form of a spray with a large contact surface and the possibility of effective absorption by the mucosa</strong> .

NutraGenix's Melatonin sublingual supplement helps you fall asleep easily and have a restful night thanks to the rapid absorption of the ingredient through the numerous mucous membranes present under the tongue. The sublingual administration of micro micelles is <strong>conveyed to the blood system</strong> much more <strong>quickly</strong> than if it had to pass through the gastrointestinal tract, as happens with the most common supplements.

The patented technology used in the <strong>NutraGenix spray supplement allows for prolonged systemic effects</strong> and is especially helpful for those who have trouble sleeping at night. This claim has been validated by an in vitro study with human epithelium on permeability. The study was conducted to compare the amount of melatonin absorbed when administered with the patented spray technology or with traditional oral tablets/powder. (Abich Test, 2020)

<span style="font-size: 18pt; line-height: 1.4; font-family: Arsenal;">COMPARED TO TRADITIONAL FORMULATIONS IT GUARANTEES:</span>
<ul>

<li> <strong>2 times higher absorption after 20 minutes (1.5% vs 2.88%)</strong>
</li>

<li> <strong>3 times higher absorption after 40 minutes (1.52% vs 4.34)</strong>
</li>


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<ul>

<li>
<strong>Greater convenience of taking</strong> : The spray is particularly <strong>convenient to use</strong> and carry. It makes dosing easy because <strong>1 spray just before going to sleep</strong> , directly under the tongue <strong>to take 1 mg of Melatonin</strong> . Because our advanced technology “does more with less”, this formula is effective at lower doses.</li>

<li> It is also <strong>suitable</strong> <strong>for those who have difficulty swallowing</strong> common capsules or tablets.</li>

<li> <strong>It is produced in a self-preserving liquid form</strong> , no preservatives or refrigeration methods are needed, and it can be kept at room temperature, making our lives easier. It can be taken in the evening at any time since the principles do not pass through the digestive system and are not affected in any way.</li>

<li>
<strong>Pleasant to the palate</strong> : The micellar structure, managing to neutralize better than other formulations the original characteristic of the principle, often unpleasant to the palate, allows the finished product to take on a pleasant taste. The Melatonin spray has a pleasant <strong>natural Vanilla aroma</strong> that can make it a valid alternative to the evening dessert.</li>

<li> NutraGenix spray <strong>has no side effects of dizziness</strong> as the morning grogginess of melatonin is due to excessive dosage.</li>

<li> Greater <strong>absorption of the ingredient</strong> : the micro micellar technology allows a high bioavailability of the ingredient (quantity of ingredient that reaches our organism), which improves as the exposure time increases. The ingredient is absorbed through the oral mucosa and therefore reaches the bloodstream much more quickly.</li>

<li>
<strong>Longer duration of the principle in our organism</strong> : The glycerol-based system allows a high stability of the dispersed active molecules and, at the same time, a rapid and prompt hydro-dispersion. The principles reach our organism more quickly and act longer in time.</li>

<li> <strong>Greater chemical stability of the active ingredients</strong> , with specific reference to oxidation, hydrolysis, colour variations, flavour stability.</li>

<li> <strong>High quality ingredients:</strong> Melatonin spray is made in Italy, is not tested on animals, is vegan, gluten-free, naturally lactose-free, without preservatives, without sweeteners, and without sugar.</li>


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